| Alnylam Pharmaceuticals, Inc. (ALNY) | 17.17% | $34.06B | 107.00% | 89.59% | 13.17 |
| BioNTech SE (BNTX) | 16.04% | $29.34B | -24.09% | 53.54% | 2.84 |
| Moderna, Inc. (MRNA) | 14.20% | $26.25B | -29.94% | 35.27% | 7.61 |
| BioMarin Pharmaceutical, Inc. (BMRN) | 8.78% | $16.16B | 19.18% | 79.57% | 6.32 |
| Sarepta Therapeutics, Inc. (SRPT) | 4.88% | $11.89B | 38.93% | 85.32% | 9.87 |
| Ionis Pharmaceuticals, Inc. (IONS) | 3.24% | $6.65B | 19.55% | 95.67% | 8.42 |
| Ultragenyx Pharmaceutical, Inc. (RARE) | 2.75% | $5.41B | 35.75% | 79.50% | 7.72 |
| BridgeBio Pharma, Inc. (BBIO) | 2.61% | $4.92B | 32.11% | 13.65% | 26.95 |
| CRISPR Therapeutics AG (CRSP) | 2.37% | $4.17B | -99.26% | -10,920.50% | 13.93 |
| Arcellx, Inc. (ACLX) | 2.16% | $4.13B | 91.47% | 95.48% | 17.35 |
| Avidity Biosciences, Inc. (RNA) | 2.07% | $4.89B | -11.70% | 66.41% | 290.34 |
| Amicus Therapeutics, Inc. (FOLD) | 1.75% | $3.35B | 34.04% | 89.39% | 7.02 |
| Genscript Biotech Corp. (1548) | 1.73% | $3.17B | 34.15% | 48.78% | 5.32 |
| Iovance Biotherapeutics, Inc. (IOVA) | 1.55% | $3.14B | 12,969.75% | -18.13% | 59.60 |
| Twist Bioscience Corp. (TWST) | 1.41% | $2.75B | 27.81% | 43.30% | 9.02 |
| Arrowhead Pharmaceuticals, Inc. (ARWR) | 1.34% | $2.67B | -100.00% | N/A | 165.61 |
| 10X Genomics, Inc. (TXG) | 1.29% | $2.38B | 4.28% | 69.82% | 3.24 |
| PTC Therapeutics, Inc. (PTCT) | 1.28% | $2.61B | -12.68% | 90.15% | 1.83 |
| ImmunityBio, Inc. (IBRX) | 1.19% | $2.49B | 2,453.66% | -320.82% | 3,917.00 |
| Beam Therapeutics, Inc. (BEAM) | 1.17% | $2.17B | -41.48% | 52.63% | 3.08 |
| Intellia Therapeutics, Inc. (NTLA) | 1.14% | $2.24B | -48.82% | 62.64% | 34.49 |
| Oxford Nanopore Technologies Plc (ONT) | 0.93% | $1.81B | -14.57% | 42.43% | 8.89 |
| Maravai Lifesciences Holdings, Inc. (MRVI) | 0.58% | $1.19B | 6.51% | 38.50% | 4.67 |
| Sana Biotechnology, Inc. (SANA) | 0.51% | $994.42M | N/A | N/A | N/A |
| 4D Molecular Therapeutics, Inc. (FDMT) | 0.45% | $844.51M | -97.91% | -32,380.00% | 30.50 |
| Arbutus Biopharma Corp. (ABUS) | 0.44% | $843.86M | -62.89% | 79.37% | 44.38 |
| CureVac NV (CVAC) | 0.42% | $771.61M | 88.41% | -215.21% | 8.25 |
| CanSino Biologics, Inc. (CASBF) | 0.41% | $737.12M | N/A | 59.56% | 5.00 |
| Wave Life Sciences Ltd. (WVE) | 0.38% | $730.96M | -10.92% | 88.97% | 4.79 |
| REGENXBIO, Inc. (RGNX) | 0.34% | $634.59M | 11.60% | 34.38% | 5.17 |
| Allogene Therapeutics, Inc. (ALLO) | 0.32% | $618.97M | -100.00% | N/A | 1,073.77 |
| Arcturus Therapeutics Holdings, Inc. (ARCT) | 0.29% | $561.13M | 380.67% | 98.04% | 2.48 |
| Entrada Therapeutics, Inc. (TRDA) | 0.27% | $557.99M | 421.16% | 99.05% | 0.42 |
| Oxford Biomedica Plc (OXB) | 0.26% | $469.39M | -36.04% | 43.78% | 2.50 |
| Verve Therapeutics, Inc. (VERV) | 0.24% | $465.43M | 219.73% | 75.09% | -4.48 |
| Fate Therapeutics, Inc. (FATE) | 0.24% | $457.79M | 625.83% | 30.29% | 14.69 |
| Absci Corp. (ABSI) | 0.23% | $442.87M | -62.28% | -166.46% | 61.36 |
| Carbios SA (ALCRB) | 0.20% | $357.22M | -65.71% | N/A | 10,249.20 |
| Voyager Therapeutics, Inc. (VYGR) | 0.18% | $340.83M | 509.48% | 95.29% | 0.92 |
| Editas Medicine, Inc. (EDIT) | 0.17% | $325.78M | -82.23% | -176.80% | 2.15 |
| PepGen Inc. (PEPG) | 0.16% | $308.95M | N/A | N/A | N/A |
| Solid Biosciences, Inc. (SLDB) | 0.16% | $306.06M | N/A | N/A | N/A |
| Poseida Therapeutics, Inc. (PSTX) | 0.15% | $298.20M | 29.78% | 94.81% | 1.46 |
| Gevo, Inc. (GEVO) | 0.15% | $280.18M | 24.12% | -59.68% | -2.38 |
| uniQure NV (QURE) | 0.15% | $275.63M | 359.37% | 8.94% | 8.22 |
| MeiraGTx Holdings Plc (MGTX) | 0.14% | $328.95M | -92.03% | -1,042.55% | 31.84 |
| Precigen, Inc. (PGEN) | 0.14% | $302.46M | -59.42% | -209.90% | 87.84 |
| Ginkgo Bioworks Holdings, Inc. (DNA) | 0.14% | $272.41M | -30.24% | 44.76% | 2.21 |
| 2seventy Bio, Inc. (TSVT) | 0.13% | $242.56M | -75.12% | 42.80% | 5.92 |
| Abeona Therapeutics, Inc. (ABEO) | 0.12% | $241.69M | -100.00% | N/A | N/A |
| Caribou Biosciences, Inc. (CRBU) | 0.10% | $191.57M | -7.75% | 75.29% | -2.60 |
| Codexis, Inc. (CDXS) | 0.10% | $197.18M | -62.58% | 41.08% | 3.07 |
| Graphite Bio, Inc. (GRPH) | 0.10% | $564.99M | N/A | N/A | N/A |
| Sangamo Therapeutics, Inc. (SGMO) | 0.10% | $176.65M | -94.79% | -622.75% | 6.06 |
| Cellectis SA (ALCLS) | 0.09% | $165.54M | 4,478.31% | 41.35% | -0.20 |
| Generation Bio Co. (GBIO) | 0.09% | $173.53M | 364.89% | 69.13% | 4.91 |
| ProQR Therapeutics NV (PRQR) | 0.08% | $151.11M | 417.56% | 88.72% | 3.09 |
| Capricor Therapeutics, Inc. (CAPR) | 0.08% | $149.35M | 1.38% | 91.01% | 4.70 |
| Adverum Biotechnologies, Inc. (ADVM) | 0.08% | $150.39M | N/A | N/A | N/A |
| Adicet Bio, Inc. (ACET) | 0.07% | $122.78M | N/A | N/A | N/A |
| Calyxt, Inc. (CLXT) | 0.06% | $126.12M | 325.38% | -106.80% | 149.21 |
| bluebird bio, Inc. (BLUE) | 0.06% | $116.76M | 680.05% | -39.26% | 9.84 |
| Aemetis, Inc. (AMTX) | 0.06% | $114.22M | 47.55% | -2.71% | 2.04 |
| Regulus Therapeutics, Inc. (RGLS) | 0.06% | $105.40M | N/A | N/A | N/A |
| Kraig Biocraft Laboratories, Inc. (KBLB) | 0.05% | $96.05M | N/A | N/A | N/A |
| Agronomics Ltd. (AGNMF) | 0.04% | $74.30M | -100.00% | N/A | N/A |
| Precision BioSciences, Inc. (DTIL) | 0.04% | $74.51M | 152.15% | 97.23% | -0.28 |
| Vor Biopharma, Inc. (VOR) | 0.04% | $71.82M | N/A | N/A | N/A |
| Benitec Biopharma, Inc. (BNTC) | 0.04% | $82.20M | -100.00% | N/A | -9.50 |
| AVROBIO, Inc. (AVRO) | 0.04% | $265.07M | N/A | N/A | N/A |
| Percheron Therapeutics Ltd. (ATHJF) | 0.03% | $54.50M | N/A | N/A | N/A |
| Atara Biotherapeutics, Inc. (ATRA) | 0.03% | $55.15M | 2,892.69% | 83.84% | 1.71 |
| Passage Bio, Inc. (PASG) | 0.03% | $49.83M | N/A | N/A | N/A |
| Gensight Biologics SA (GSGTF) | 0.02% | $43.85M | -50.93% | N/A | 30.40 |
| Dyadic International, Inc. (DYAI) | 0.02% | $36.55M | -53.90% | 21.75% | 21.52 |
| Vascular Biogenics Ltd. (VBLT) | 0.02% | $4.62M | N/A | -3,100.00% | 5.54 |
| MediGene AG (MDG1) | 0.02% | $15.79M | -80.69% | 49.40% | 4.26 |
| Evogene Ltd. (EVGN) | 0.01% | $14.57M | 42.61% | -25.82% | N/A |
| Senti Biosciences, Inc. (SNTI) | 0.01% | $14.06M | -100.00% | N/A | 96.15 |
| Celyad Oncology SA (CYAD) | 0.01% | $10.66M | N/A | 871.57% | 203.10 |
| Willow Biosciences, Inc. (CANSF) | <0.01% | $10.62M | 660.00% | 65.59% | 7.95 |
| Mustang Bio, Inc. (MBIO) | <0.01% | $9.82M | N/A | N/A | N/A |
| Evolva Holding SA (EVE) | <0.01% | $7.28M | 57.32% | N/A | 6.29 |
| BacTech Environmental Corp. (BAC) | <0.01% | $4.27M | N/A | N/A | N/A |
| Arcadia Biosciences, Inc. (RKDA) | <0.01% | $3.80M | -5.98% | 51.53% | -0.63 |
| AquaBounty Technologies, Inc. (AQB) | <0.01% | $3.87M | -77.15% | -892.36% | 8.36 |
| Alaunos Therapeutics, Inc. (TCRT) | <0.01% | $3.73M | N/A | 75.00% | 1,454.96 |
| Sorrento Therapeutics, Inc. (SRNE) | <0.01% | $2.48M | 18.78% | N/A | 7.21 |
| Cult Food Science Corp. (CULT) | <0.01% | $4.12M | N/A | N/A | N/A |
| Atlantic International Corp. (SQL) | <0.01% | $302.12M | N/A | 9.79% | 2.38 |
| Bio-Path Holdings, Inc. (BPTH) | <0.01% | $2.60M | N/A | N/A | N/A |
| Phio Pharmaceuticals Corp. (PHIO) | <0.01% | $2.83M | N/A | N/A | N/A |
| Eat & Beyond Global Holdings, Inc. (EATS) | <0.01% | $1.36M | 413.89% | 100.00% | -101.89 |
| Yield10 Bioscience, Inc. (YTEN) | <0.01% | $0.80M | N/A | 86.67% | 3.73 |
