| Alnylam Pharmaceuticals, Inc. (ALNY) | 29.12% | $58.49B | 149.35% | 83.98% | 19.53 |
| BioNTech SE (BNTX) | 12.44% | $24.80B | 29.80% | 90.24% | 2.01 |
| BridgeBio Pharma, Inc. (BBIO) | 5.93% | $11.91B | 4,318.01% | 93.98% | 34.01 |
| Ionis Pharmaceuticals, Inc. (IONS) | 5.88% | $11.91B | 17.12% | 96.67% | 10.60 |
| Avidity Biosciences, Inc. (RNA) | 5.11% | $10.19B | 88.12% | 78.84% | 233.32 |
| BioMarin Pharmaceutical, Inc. (BMRN) | 4.96% | $9.89B | 5.98% | 81.58% | 3.09 |
| Moderna, Inc. (MRNA) | 4.79% | $9.59B | -45.44% | 74.51% | 2.82 |
| PTC Therapeutics, Inc. (PTCT) | 2.86% | $5.76B | 7.23% | 88.95% | 2.29 |
| Arrowhead Pharmaceuticals, Inc. (ARWR) | 2.72% | $5.42B | N/A | 77.59% | 3.50 |
| CRISPR Therapeutics AG (CRSP) | 2.52% | $5.01B | 72.53% | -5,477.69% | 71.64 |
| Arcellx, Inc. (ACLX) | 2.41% | $5.00B | -80.99% | 62.76% | 118.01 |
| Genscript Biotech Corp. (1548) | 2.25% | $4.48B | -28.87% | 46.20% | 3.81 |
| Ultragenyx Pharmaceutical, Inc. (RARE) | 1.48% | $2.96B | 14.65% | 77.12% | 5.45 |
| Amicus Therapeutics, Inc. (FOLD) | 1.37% | $2.74B | 19.46% | 87.38% | 4.38 |
| Beam Therapeutics, Inc. (BEAM) | 1.13% | $2.25B | -32.03% | 42.67% | 28.11 |
| ImmunityBio, Inc. (IBRX) | 1.01% | $2.10B | 425.07% | 87.12% | 35.53 |
| Twist Bioscience Corp. (TWST) | 0.92% | $1.83B | 17.91% | 53.40% | 5.73 |
| Oxford Nanopore Technologies Plc (ONT) | 0.89% | $1.77B | 7.97% | 44.46% | 4.72 |
| 10X Genomics, Inc. (TXG) | 0.88% | $1.90B | -1.75% | 67.32% | 1.67 |
| Sarepta Therapeutics, Inc. (SRPT) | 0.86% | $1.85B | -14.52% | 57.63% | 0.97 |
| uniQure NV (QURE) | 0.77% | $1.71B | -52.71% | 18.55% | 63.40 |
| CanSino Biologics, Inc. (CASBF) | 0.70% | $1.72B | 18.16% | 78.37% | 10.58 |
| Wave Life Sciences Ltd. (WVE) | 0.63% | $1.25B | -55.82% | 74.76% | 9.44 |
| CureVac NV (CVAC) | 0.59% | $1.17B | -93.00% | -538.41% | 0.33 |
| Precigen, Inc. (PGEN) | 0.58% | $1.16B | 19.39% | -64.72% | 91.53 |
| Sana Biotechnology, Inc. (SANA) | 0.53% | $1.06B | N/A | N/A | N/A |
| Intellia Therapeutics, Inc. (NTLA) | 0.51% | $1.10B | 51.27% | 64.19% | 23.14 |
| Oxford Biomedica Plc (OXB) | 0.49% | $980.60M | 43.84% | 40.65% | 3.77 |
| Arbutus Biopharma Corp. (ABUS) | 0.43% | $862.64M | 522.19% | 99.90% | 32.53 |
| Iovance Biotherapeutics, Inc. (IOVA) | 0.42% | $913.03M | 15.20% | 29.61% | 2.16 |
| MeiraGTx Holdings Plc (MGTX) | 0.34% | $681.39M | 1,208.87% | -58.93% | 15.13 |
| Graphite Bio, Inc. (GRPH) | 0.33% | $656.67M | N/A | 99.00% | 64.47 |
| REGENXBIO, Inc. (RGNX) | 0.28% | $567.48M | 22.88% | 67.68% | 3.05 |
| Gevo, Inc. (GEVO) | 0.27% | $529.63M | 725.34% | 42.25% | 4.52 |
| Absci Corp. (ABSI) | 0.25% | $498.66M | -53.31% | -405.90% | 48.73 |
| 4D Molecular Therapeutics, Inc. (FDMT) | 0.25% | $490.38M | 200.00% | -12,486.67% | -1,898.74 |
| Ginkgo Bioworks Holdings, Inc. (DNA) | 0.21% | $537.36M | -56.39% | 38.28% | 3.11 |
| Maravai Lifesciences Holdings, Inc. (MRVI) | 0.21% | $732.89M | -36.15% | 13.58% | N/A |
| AVROBIO, Inc. (AVRO) | 0.18% | $361.52M | N/A | N/A | N/A |
| Benitec Biopharma, Inc. (BNTC) | 0.17% | $335.74M | N/A | N/A | N/A |
| Solid Biosciences, Inc. (SLDB) | 0.16% | $316.32M | N/A | N/A | N/A |
| Capricor Therapeutics, Inc. (CAPR) | 0.14% | $271.10M | -100.00% | N/A | 25.05 |
| Entrada Therapeutics, Inc. (TRDA) | 0.13% | $264.09M | -91.75% | 25.65% | -0.55 |
| Allogene Therapeutics, Inc. (ALLO) | 0.13% | $265.18M | N/A | N/A | N/A |
| Cellectis SA (ALCLS) | 0.12% | $237.87M | 96.91% | 70.00% | 1.10 |
| Arcturus Therapeutics Holdings, Inc. (ARCT) | 0.12% | $236.79M | -46.69% | 96.74% | 1.17 |
| Voyager Therapeutics, Inc. (VYGR) | 0.12% | $234.63M | -82.42% | 79.52% | 0.17 |
| ProQR Therapeutics NV (PRQR) | 0.12% | $233.57M | -20.23% | 76.72% | N/A |
| Editas Medicine, Inc. (EDIT) | 0.11% | $222.10M | 597.47% | 48.74% | 2.19 |
| Abeona Therapeutics, Inc. (ABEO) | 0.11% | $215.37M | N/A | -117.00% | 441.85 |
| Caribou Biosciences, Inc. (CRBU) | 0.10% | $194.63M | -23.01% | 56.24% | -4.48 |
| Carbios SA (ALCRB) | 0.08% | $157.29M | 466.67% | N/A | 482.21 |
| Codexis, Inc. (CDXS) | 0.08% | $152.65M | -32.98% | 56.02% | 4.34 |
| PepGen Inc. (PEPG) | 0.08% | $317.57M | N/A | N/A | N/A |
| Atlantic International Corp. (SQL) | 0.07% | $143.60M | -1.66% | 9.50% | 0.42 |
| Sangamo Therapeutics, Inc. (SGMO) | 0.07% | $158.76M | -98.82% | -226.68% | 6.08 |
| Aemetis, Inc. (AMTX) | 0.07% | $132.81M | -27.32% | -0.10% | 2.11 |
| Vor Biopharma, Inc. (VOR) | 0.06% | $127.93M | N/A | N/A | N/A |
| Fate Therapeutics, Inc. (FATE) | 0.06% | $123.40M | -71.84% | -71.89% | -1.03 |
| Agronomics Ltd. (AGNMF) | 0.05% | $103.18M | N/A | N/A | N/A |
| Kraig Biocraft Laboratories, Inc. (KBLB) | 0.05% | $98.80M | N/A | N/A | N/A |
| Adverum Biotechnologies, Inc. (ADVM) | 0.05% | $90.65M | N/A | N/A | 93.00 |
| Atara Biotherapeutics, Inc. (ATRA) | 0.04% | $82.94M | -38.63% | 96.85% | 0.70 |
| Precision BioSciences, Inc. (DTIL) | 0.04% | $81.40M | -97.74% | -5,084.62% | 70.91 |
| Calyxt, Inc. (CLXT) | 0.03% | $68.75M | 11.34% | -68.81% | 56.80 |
| Adicet Bio, Inc. (ACET) | 0.03% | $98.02M | N/A | N/A | N/A |
| Senti Biosciences, Inc. (SNTI) | 0.03% | $51.01M | N/A | N/A | N/A |
| Atlas Energy Corp. (CANSF) | 0.02% | $39.92M | -100.00% | N/A | -1.59 |
| Generation Bio Co. (GBIO) | 0.02% | $34.43M | -78.90% | 11.92% | -1.46 |
| Dyadic International, Inc. (DYAI) | 0.02% | $33.82M | 150.49% | 36.52% | 6.84 |
| Gensight Biologics SA (GSGTF) | 0.01% | $25.97M | 18.39% | N/A | 25.20 |
| Passage Bio, Inc. (PASG) | 0.01% | $19.61M | N/A | N/A | N/A |
| Evogene Ltd. (EVGN) | 0.01% | $10.02M | -7.13% | 51.81% | 2.21 |
| Celyad Oncology SA (CYAD) | 0.01% | $10.12M | 82.35% | 494.09% | 230.29 |
| Phio Pharmaceuticals Corp. (PHIO) | <0.01% | $8.93M | N/A | N/A | N/A |
| EvoNext Holdings SA (EVE) | <0.01% | $8.09M | -100.00% | N/A | N/A |
| Mustang Bio, Inc. (MBIO) | <0.01% | $8.83M | N/A | N/A | N/A |
| Alaunos Therapeutics, Inc. (TCRT) | <0.01% | $5.71M | -100.00% | N/A | 875.21 |
| Arcadia Biosciences, Inc. (RKDA) | <0.01% | $5.04M | 11.41% | 43.37% | 0.27 |
| Sorrento Therapeutics, Inc. (SRNE) | <0.01% | $4.96M | 18.78% | N/A | 7.21 |
| Percheron Therapeutics Ltd. (ATHJF) | <0.01% | $4.94M | N/A | N/A | N/A |
| BacTech Environmental Corp. (BAC) | <0.01% | $4.10M | N/A | N/A | N/A |
| AquaBounty Technologies, Inc. (AQB) | <0.01% | $4.07M | -100.00% | N/A | N/A |
| Digital Asset Technologies, Inc. (EATS) | <0.01% | $2.10M | -100.00% | N/A | -1,850.88 |
| Cult Food Science Corp. (CULT) | <0.01% | $1.00M | N/A | -488.75% | 496.66 |
| MediGene AG (MDG1) | <0.01% | $0.81M | -80.69% | N/A | 3.93 |
| Bio-Path Holdings, Inc. (BPTH) | <0.01% | $0.72M | N/A | N/A | N/A |
