| Alnylam Pharmaceuticals, Inc. (ALNY) | 24.51% | $41.06B | 20.20% | 88.04% | 14.95 |
| BioNTech SE (BNTX) | 16.59% | $27.14B | -5.51% | 54.16% | 2.48 |
| Moderna, Inc. (MRNA) | 7.77% | $13.01B | -35.33% | -19.44% | 1.80 |
| BioMarin Pharmaceutical, Inc. (BMRN) | 6.65% | $11.14B | 12.72% | 79.31% | 4.53 |
| BridgeBio Pharma, Inc. (BBIO) | 5.27% | $8.82B | -44.76% | 97.15% | 65.92 |
| Ionis Pharmaceuticals, Inc. (IONS) | 3.96% | $6.64B | 10.14% | 94.79% | 6.41 |
| CRISPR Therapeutics AG (CRSP) | 2.93% | $4.91B | 71.63% | -7,095.95% | 34.11 |
| Genscript Biotech Corp. (1548) | 2.46% | $4.13B | -28.87% | 46.20% | 3.81 |
| PTC Therapeutics, Inc. (PTCT) | 2.30% | $3.85B | 459.73% | 98.58% | 1.56 |
| Arcellx, Inc. (ACLX) | 2.27% | $3.80B | -79.29% | 80.61% | 40.81 |
| Avidity Biosciences, Inc. (RNA) | 2.26% | $3.79B | -55.60% | 50.10% | 273.44 |
| Ultragenyx Pharmaceutical, Inc. (RARE) | 1.67% | $2.79B | 27.99% | 72.97% | 6.57 |
| Arrowhead Pharmaceuticals, Inc. (ARWR) | 1.51% | $2.53B | N/A | 98.88% | 2.49 |
| ImmunityBio, Inc. (IBRX) | 1.48% | $2.48B | 41,192.50% | 76.47% | 106.65 |
| Twist Bioscience Corp. (TWST) | 1.36% | $2.28B | 23.23% | 49.60% | 6.23 |
| Beam Therapeutics, Inc. (BEAM) | 1.27% | $2.13B | 0.81% | 26.00% | 10.32 |
| Oxford Nanopore Technologies Plc (ONT) | 1.16% | $1.94B | 7.97% | 44.46% | 4.72 |
| Amicus Therapeutics, Inc. (FOLD) | 1.12% | $1.88B | 13.45% | 89.19% | 4.98 |
| Sarepta Therapeutics, Inc. (SRPT) | 1.07% | $1.79B | 80.15% | 80.19% | 3.15 |
| 10X Genomics, Inc. (TXG) | 0.85% | $1.60B | 9.84% | 70.64% | 1.16 |
| CanSino Biologics, Inc. (CASBF) | 0.74% | $1.44B | 18.04% | 82.40% | 7.61 |
| CureVac NV (CVAC) | 0.73% | $1.23B | -93.00% | -538.41% | 0.33 |
| Intellia Therapeutics, Inc. (NTLA) | 0.71% | $1.19B | -42.54% | 84.98% | 7.71 |
| Wave Life Sciences Ltd. (WVE) | 0.71% | $1.20B | -26.82% | 76.41% | 10.50 |
| Verve Therapeutics, Inc. (VERV) | 0.59% | $983.25M | 479.03% | 94.80% | -0.38 |
| Graphite Bio, Inc. (GRPH) | 0.57% | $955.21M | N/A | N/A | N/A |
| Sana Biotechnology, Inc. (SANA) | 0.56% | $942.82M | N/A | N/A | N/A |
| uniQure NV (QURE) | 0.47% | $788.38M | -81.53% | -201.47% | 33.01 |
| MeiraGTx Holdings Plc (MGTX) | 0.41% | $680.69M | 176.33% | -131.52% | 15.94 |
| Iovance Biotherapeutics, Inc. (IOVA) | 0.37% | $624.46M | 6,798.46% | -12.32% | 3.61 |
| Arbutus Biopharma Corp. (ABUS) | 0.36% | $607.14M | 15.14% | 81.29% | 87.22 |
| Precigen, Inc. (PGEN) | 0.32% | $540.18M | 25.92% | -5.82% | 93.45 |
| Oxford Biomedica Plc (OXB) | 0.30% | $505.72M | 43.84% | 40.65% | 3.77 |
| Ginkgo Bioworks Holdings, Inc. (DNA) | 0.28% | $584.15M | 27.34% | 43.27% | 0.92 |
| REGENXBIO, Inc. (RGNX) | 0.26% | $437.37M | 469.79% | 91.70% | 1.49 |
| AVROBIO, Inc. (AVRO) | 0.25% | $422.62M | N/A | N/A | N/A |
| Solid Biosciences, Inc. (SLDB) | 0.24% | $407.73M | N/A | N/A | N/A |
| Maravai Lifesciences Holdings, Inc. (MRVI) | 0.23% | $695.22M | -27.00% | 15.21% | 2.43 |
| Arcturus Therapeutics Holdings, Inc. (ARCT) | 0.22% | $373.72M | -21.84% | 96.86% | 0.57 |
| Gevo, Inc. (GEVO) | 0.21% | $356.95M | 629.55% | 4.94% | 9.01 |
| Capricor Therapeutics, Inc. (CAPR) | 0.21% | $349.21M | -100.00% | N/A | 16.87 |
| Absci Corp. (ABSI) | 0.20% | $340.58M | 31.29% | -160.56% | 35.57 |
| Benitec Biopharma, Inc. (BNTC) | 0.20% | $335.48M | N/A | N/A | N/A |
| Vor Biopharma, Inc. (VOR) | 0.19% | $312.40M | N/A | N/A | N/A |
| Abeona Therapeutics, Inc. (ABEO) | 0.18% | $293.64M | N/A | N/A | N/A |
| Allogene Therapeutics, Inc. (ALLO) | 0.17% | $279.98M | -100.00% | N/A | N/A |
| Entrada Therapeutics, Inc. (TRDA) | 0.15% | $248.59M | -65.23% | 95.40% | 0.27 |
| Codexis, Inc. (CDXS) | 0.15% | $247.71M | -55.82% | 48.43% | 4.43 |
| ProQR Therapeutics NV (PRQR) | 0.15% | $244.09M | -1.53% | 85.00% | 0.65 |
| Editas Medicine, Inc. (EDIT) | 0.14% | $241.09M | 310.40% | 58.84% | -2.61 |
| 4D Molecular Therapeutics, Inc. (FDMT) | 0.12% | $198.27M | -50.00% | -12,428.57% | -5,110.03 |
| Voyager Therapeutics, Inc. (VYGR) | 0.12% | $193.12M | -66.83% | 84.33% | 0.05 |
| Aemetis, Inc. (AMTX) | 0.10% | $162.79M | -40.96% | -11.85% | 2.35 |
| Caribou Biosciences, Inc. (CRBU) | 0.09% | $151.60M | -3.13% | 50.49% | -9.84 |
| Carbios SA (ALCRB) | 0.08% | $140.19M | 466.67% | N/A | 482.21 |
| Fate Therapeutics, Inc. (FATE) | 0.08% | $131.83M | -15.38% | -104.60% | -4.77 |
| Atlantic International Corp. (SQL) | 0.08% | $133.78M | N/A | 9.24% | 0.64 |
| Agronomics Ltd. (AGNMF) | 0.08% | $125.71M | N/A | N/A | N/A |
| Sangamo Therapeutics, Inc. (SGMO) | 0.07% | $120.74M | 1,238.25% | 70.11% | 2.26 |
| Cellectis SA (ALCLS) | 0.07% | $114.21M | 142.67% | N/A | -0.11 |
| Kraig Biocraft Laboratories, Inc. (KBLB) | 0.05% | $91.55M | N/A | N/A | N/A |
| Atara Biotherapeutics, Inc. (ATRA) | 0.04% | $62.72M | 258.77% | 79.18% | 0.66 |
| Adicet Bio, Inc. (ACET) | 0.04% | $61.99M | N/A | N/A | N/A |
| Senti Biosciences, Inc. (SNTI) | 0.03% | $55.55M | N/A | N/A | N/A |
| Adverum Biotechnologies, Inc. (ADVM) | 0.03% | $53.06M | N/A | N/A | 101.59 |
| Calyxt, Inc. (CLXT) | 0.03% | $50.95M | 89.72% | -58.03% | 60.85 |
| Precision BioSciences, Inc. (DTIL) | 0.03% | $49.34M | -99.84% | -2,331.03% | -0.06 |
| PepGen Inc. (PEPG) | 0.02% | $41.23M | N/A | N/A | N/A |
| Dyadic International, Inc. (DYAI) | 0.02% | $29.77M | 17.62% | 24.37% | 10.71 |
| Generation Bio Co. (GBIO) | 0.02% | $25.90M | 114.91% | 86.98% | -1.74 |
| Passage Bio, Inc. (PASG) | 0.01% | $24.92M | N/A | N/A | N/A |
| Gensight Biologics SA (GSGTF) | 0.01% | $22.31M | 18.39% | N/A | 25.20 |
| Celyad Oncology SA (CYAD) | 0.01% | $17.91M | 82.35% | 494.09% | 230.29 |
| Phio Pharmaceuticals Corp. (PHIO) | 0.01% | $11.08M | N/A | N/A | N/A |
| Evolva Holding SA (EVE) | 0.01% | $10.09M | -100.00% | N/A | N/A |
| Mustang Bio, Inc. (MBIO) | 0.01% | $11.60M | N/A | N/A | N/A |
| Evogene Ltd. (EVGN) | 0.01% | $11.94M | -42.49% | 10.27% | 2.59 |
| Alaunos Therapeutics, Inc. (TCRT) | <0.01% | $9.87M | 100.00% | N/A | 203.48 |
| Arcadia Biosciences, Inc. (RKDA) | <0.01% | $6.53M | -4.38% | 43.17% | 0.17 |
| Percheron Therapeutics Ltd. (ATHJF) | <0.01% | $6.43M | N/A | N/A | N/A |
| BacTech Environmental Corp. (BAC) | <0.01% | $5.64M | N/A | N/A | N/A |
| Digital Asset Technologies, Inc. (EATS) | <0.01% | $6.72M | -100.00% | N/A | -1,850.88 |
| Atlas Energy Corp. (CANSF) | <0.01% | $60.41M | 3,349.02% | 99.20% | 0.32 |
| AquaBounty Technologies, Inc. (AQB) | <0.01% | $3.00M | -100.00% | N/A | N/A |
| MediGene AG (MDG1) | <0.01% | $2.07M | -80.69% | N/A | 3.93 |
| Bio-Path Holdings, Inc. (BPTH) | <0.01% | $1.40M | N/A | N/A | N/A |
| Sorrento Therapeutics, Inc. (SRNE) | <0.01% | $1.32M | 18.78% | N/A | 7.21 |
| Cult Food Science Corp. (CULT) | <0.01% | $1.02M | N/A | 21.07% | 1,003.24 |
