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LUX CAPITAL
The Lux Bio + Tech Index

LUXBT

Index Performance

-8.84%
LUXBT
-2.42%
IBB
+5.29%
SPY

Overview

Description

Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingCustom
  • # of holdings53
What's inside?

Holdings

All holdings as of May 24, 2024
CSV download
Janux Therapeutics, Inc. (JANX)7.99%$2.35B-38.87%57.51%167.30
BridgeBio Pharma, Inc. (BBIO)7.04%$5.23B11,461.88%99.10%30.87
Third Harmonic Bio, Inc. (THRD)5.72%$572.88MN/AN/AN/A
Dyne Therapeutics, Inc. (DYN)5.08%$3.06BN/AN/AN/A
Sana Biotechnology, Inc. (SANA)3.92%$1.78BN/AN/AN/A
Nuvalent, Inc. (NUVL)3.83%$4.02BN/AN/AN/A
Nkarta, Inc. (NKTX)3.60%$453.81MN/AN/AN/A
Nuvation Bio, Inc. (NUVB)3.54%$761.29MN/AN/AN/A
Recursion Pharmaceuticals, Inc. (RXRX)3.05%$2.11B13.68%-5.60%45.52
Nurix Therapeutics, Inc. (NRIX)2.88%$899.85M30.74%76.56%5.73
Stoke Therapeutics, Inc. (STOK)2.43%$751.05M-18.17%73.60%57.63
Schrödinger, Inc. (SDGR)2.32%$1.40B-43.51%51.61%8.71
Regeneron Pharmaceuticals, Inc. (REGN)2.12%$106.74B-0.54%82.58%7.86
Certara, Inc. (CERT)2.03%$2.69B7.04%45.91%8.14
ATAI Life Sciences NV (ATAI)2.01%$269.52M-100.00%N/A790.37
CRISPR Therapeutics AG (CRSP)1.98%$4.69B-99.50%-10,177.58%13.62
Tango Therapeutics, Inc. (TNGX)1.75%$738.31M12.23%90.34%14.87
Revolution Medicines, Inc. (RVMD)1.65%$6.26B-100.00%N/A808.96
Ionis Pharmaceuticals, Inc. (IONS)1.62%$5.44B-8.45%93.47%7.81
Kymera Therapeutics, Inc. (KYMR)1.61%$2.09B8.67%85.42%30.37
ProKidney Corp. (DNAC)1.57%$215.42MN/AN/AN/A
Alector, Inc. (ALEC)1.57%$480.96M-3.96%85.58%0.42
Roivant Sciences Ltd. (ROIV)1.56%$8.85B117.80%82.20%30.90
Exscientia Plc (EXAI)1.53%$592.32M-4.18%-126.52%13.28
Denali Therapeutics, Inc. (DNLI)1.44%$2.74B-100.00%N/A7.38
4D Molecular Therapeutics, Inc. (FDMT)1.44%$1.30B-90.60%-5,592.86%51.06
Compass Pathways Plc (CMPS)1.42%$511.20MN/AN/AN/A
Olink Holding AB (OLK)1.41%$2.98B3.95%60.68%16.58
Moderna, Inc. (MRNA)1.39%$63.85B-91.07%20.96%6.49
Lyell Immunopharma, Inc. (LYEL)1.36%$706.18M-95.38%-167,366.67%1,507.47
10X Genomics, Inc. (TXG)1.28%$2.39B5.01%67.78%6.72
Fate Therapeutics, Inc. (FATE)1.27%$400.69M-96.74%-150.44%71.11
Intellia Therapeutics, Inc. (NTLA)1.18%$2.40B129.53%91.32%37.01
Century Therapeutics, Inc. (IPSC)1.16%$252.86M-50.29%-277.31%83.83
Arvinas, Inc. (ARVN)1.14%$2.41B-22.15%93.28%25.07
Evotec SE (EVO)1.12%$1.70BN/A16.65%3.45
Editas Medicine, Inc. (EDIT)1.12%$463.00M-88.48%-24.14%4.98
Caribou Biosciences, Inc. (CRBU)0.92%$268.24M-30.64%70.77%5.77
Erasca, Inc. (ERAS)0.91%$717.51MN/AN/AN/A
Ultragenyx Pharmaceutical, Inc. (RARE)0.88%$3.35B8.30%75.76%10.05
Vir Biotechnology, Inc. (VIR)0.86%$1.44B-10.45%91.88%4.13
Beam Therapeutics, Inc. (BEAM)0.85%$2.00B-69.39%26.71%4.91
Verve Therapeutics, Inc. (VERV)0.75%$414.74M305.63%71.34%35.60
BioNTech SE (BNTX)0.72%$23.05B-85.14%68.50%4.32
Seer, Inc. (California) (SEER)0.68%$118.13M-24.35%-4.34%-10.26
Alnylam Pharmaceuticals, Inc. (ALNY)0.66%$18.69B54.82%86.65%9.57
AbCellera Biologics, Inc. (ABCL)0.64%$1.13B-18.36%32.03%18.91
Relay Therapeutics, Inc. (RLAY)0.63%$905.30M4,327.88%86.06%11.00
Ginkgo Bioworks Holdings, Inc. (DNA)0.57%$1.13B-52.98%41.83%8.22
Prime Medicine, Inc. (PRME)0.55%$831.21MN/A-122.50%954.88
Adaptive Biotechnologies Corp. (ADPT)0.52%$506.95M11.23%50.35%2.22
SAGE Therapeutics, Inc. (SAGE)0.49%$708.94M139.89%83.94%4.52
Seres Therapeutics, Inc. (MCRB)0.26%$138.82MN/AN/A1.70
Market data by FactSet