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LUX CAPITAL
The Lux Bio + Tech Index

LUXBT

Index Performance

+12.59%
LUXBT
+17.00%
IBB
+7.28%
SPY

Overview

Description

Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingCustom
  • # of holdings52
What's inside?

Holdings

All holdings as of July 26, 2024
CSV download
Janux Therapeutics, Inc. (JANX)7.28%$2.22B-38.87%57.51%167.30
Dyne Therapeutics, Inc. (DYN)6.82%$4.18BN/AN/AN/A
BridgeBio Pharma, Inc. (BBIO)6.50%$5.00B11,461.88%99.10%30.87
Third Harmonic Bio, Inc. (THRD)4.81%$514.33MN/AN/AN/A
Nuvalent, Inc. (NUVL)4.36%$4.73BN/AN/AN/A
Nuvation Bio, Inc. (NUVB)4.06%$913.90MN/AN/AN/A
Nurix Therapeutics, Inc. (NRIX)3.93%$1.36B-60.58%66.17%9.12
Nkarta, Inc. (NKTX)3.70%$486.93MN/AN/AN/A
Sana Biotechnology, Inc. (SANA)2.98%$1.34BN/AN/AN/A
Recursion Pharmaceuticals, Inc. (RXRX)2.65%$2.10B13.68%-5.60%45.52
Stoke Therapeutics, Inc. (STOK)2.52%$758.88M-18.17%73.60%57.63
Tango Therapeutics, Inc. (TNGX)2.34%$1.05B12.23%90.34%14.87
Schrödinger, Inc. (SDGR)2.28%$1.42B-43.51%51.61%8.71
Regeneron Pharmaceuticals, Inc. (REGN)2.21%$115.32B-0.54%82.58%7.86
Ionis Pharmaceuticals, Inc. (IONS)2.12%$7.57B-8.45%93.47%7.81
Kymera Therapeutics, Inc. (KYMR)1.99%$2.70B8.67%85.42%30.37
CRISPR Therapeutics AG (CRSP)1.97%$4.89B-99.50%-10,177.58%13.62
Alector, Inc. (ALEC)1.94%$625.54M-3.96%85.58%0.42
ATAI Life Sciences NV (ATAI)1.89%$264.50M-100.00%N/A790.37
Revolution Medicines, Inc. (RVMD)1.89%$7.52B-100.00%N/A808.96
Fate Therapeutics, Inc. (FATE)1.86%$614.69M-96.74%-150.44%71.11
Certara, Inc. (CERT)1.81%$2.50B7.04%45.91%8.14
Denali Therapeutics, Inc. (DNLI)1.72%$3.44B-100.00%N/A7.38
Exscientia Plc (EXAI)1.67%$659.26M-4.18%-126.52%13.28
Roivant Sciences Ltd. (ROIV)1.47%$7.93B103.65%77.59%25.63
Compass Pathways Plc (CMPS)1.46%$509.84MN/AN/AN/A
Intellia Therapeutics, Inc. (NTLA)1.21%$2.55B129.53%91.32%37.01
ProKidney Corp. (DNAC)1.13%$276.95MN/AN/AN/A
10X Genomics, Inc. (TXG)1.13%$2.10B5.01%67.78%6.72
Beam Therapeutics, Inc. (BEAM)1.11%$2.65B-69.39%26.71%4.91
Evotec SE (EVO)1.09%$1.67BN/A16.65%3.45
Editas Medicine, Inc. (EDIT)1.08%$458.07M-88.48%-24.14%4.98
Erasca, Inc. (ERAS)1.07%$849.69MN/AN/AN/A
Verve Therapeutics, Inc. (VERV)1.02%$628.06M305.63%71.34%35.60
Alnylam Pharmaceuticals, Inc. (ALNY)0.99%$30.09B54.82%86.65%9.57
4D Molecular Therapeutics, Inc. (FDMT)0.99%$957.55M-90.60%-5,592.86%51.06
Moderna, Inc. (MRNA)0.97%$46.14B-91.07%20.96%6.49
Ultragenyx Pharmaceutical, Inc. (RARE)0.93%$4.08B8.30%75.76%10.05
Arvinas, Inc. (ARVN)0.91%$2.02B-22.15%93.28%25.07
Century Therapeutics, Inc. (IPSC)0.90%$201.11M-50.29%-277.31%83.83
Vir Biotechnology, Inc. (VIR)0.83%$1.45B-10.45%91.88%4.13
Relay Therapeutics, Inc. (RLAY)0.79%$1.20B4,327.88%86.06%11.00
Lyell Immunopharma, Inc. (LYEL)0.77%$415.55M-95.38%-167,366.67%1,507.47
Caribou Biosciences, Inc. (CRBU)0.77%$220.38M-30.64%70.77%5.77
Seer, Inc. (California) (SEER)0.69%$125.44M-24.35%-4.34%-10.26
Adaptive Biotechnologies Corp. (ADPT)0.65%$638.10M11.23%50.35%2.22
BioNTech SE (BNTX)0.62%$20.13B-85.14%68.50%4.32
AbCellera Biologics, Inc. (ABCL)0.52%$911.57M-18.36%32.03%18.91
SAGE Therapeutics, Inc. (SAGE)0.44%$630.11M139.89%83.94%4.52
Prime Medicine, Inc. (PRME)0.43%$678.17MN/A-122.50%954.88
Seres Therapeutics, Inc. (MCRB)0.37%$205.97MN/AN/A1.70
Ginkgo Bioworks Holdings, Inc. (DNA)0.33%$582.26M-52.98%41.83%8.22
Market data by FactSet