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LUX CAPITAL
The Lux Bio + Tech Index

LUXBT

Index Performance

+4.18%
LUXBT
+9.78%
IBB
+2.68%
SPY

Overview

Description

Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingCustom
  • # of holdings52
What's inside?

Holdings

All holdings as of September 18, 2024
CSV download
Janux Therapeutics, Inc. (JANX)8.68%$2.52B741.72%94.31%109.64
BridgeBio Pharma, Inc. (BBIO)6.77%$4.88B32.11%13.65%26.95
Nuvalent, Inc. (NUVL)5.95%$6.61BN/AN/AN/A
Dyne Therapeutics, Inc. (DYN)5.71%$3.45BN/AN/AN/A
Third Harmonic Bio, Inc. (THRD)5.67%$554.82MN/AN/AN/A
Nurix Therapeutics, Inc. (NRIX)4.81%$1.59B-60.58%66.17%9.12
Nuvation Bio, Inc. (NUVB)3.42%$719.91MN/A-10.87%297.62
Nkarta, Inc. (NKTX)3.01%$371.84MN/AN/AN/A
Stoke Therapeutics, Inc. (STOK)2.63%$801.30MN/A77.02%31.48
Regeneron Pharmaceuticals, Inc. (REGN)2.53%$123.47B12.32%83.06%8.46
Denali Therapeutics, Inc. (DNLI)2.39%$4.40B-100.00%N/A2,425.39
Recursion Pharmaceuticals, Inc. (RXRX)2.38%$1.94B30.86%9.14%28.81
Kymera Therapeutics, Inc. (KYMR)2.25%$2.96B55.33%92.59%19.87
Schrödinger, Inc. (SDGR)2.17%$1.25B34.51%66.20%5.73
Sana Biotechnology, Inc. (SANA)2.17%$954.38MN/AN/AN/A
Tango Therapeutics, Inc. (TNGX)2.16%$887.16M36.15%96.82%15.17
Revolution Medicines, Inc. (RVMD)1.95%$7.36B-100.00%N/A6,611.66
Ionis Pharmaceuticals, Inc. (IONS)1.90%$6.68B19.55%95.67%8.42
CRISPR Therapeutics AG (CRSP)1.83%$4.22B-99.26%-10,920.50%13.93
Alector, Inc. (ALEC)1.83%$548.89M-73.17%84.88%-0.51
Roivant Sciences Ltd. (ROIV)1.77%$8.87B154.96%88.19%21.58
Exscientia Plc (EXAI)1.76%$674.71M48.17%-180.33%11.40
ATAI Life Sciences NV (ATAI)1.60%$208.07M58.72%69.96%339.14
Compass Pathways Plc (CMPS)1.44%$499.23MN/AN/AN/A
Fate Therapeutics, Inc. (FATE)1.44%$441.85M625.83%30.29%14.69
Certara, Inc. (CERT)1.37%$1.76B3.17%43.20%6.36
10X Genomics, Inc. (TXG)1.34%$2.35B4.28%69.82%3.24
Ultragenyx Pharmaceutical, Inc. (RARE)1.30%$5.32B35.75%79.50%7.72
Alnylam Pharmaceuticals, Inc. (ALNY)1.25%$35.07B107.00%89.59%13.17
ProKidney Corp. (DNAC)1.19%$301.26MN/AN/AN/A
Intellia Therapeutics, Inc. (NTLA)1.12%$2.29B-48.82%62.64%34.49
Erasca, Inc. (ERAS)1.03%$816.44MN/AN/AN/A
4D Molecular Therapeutics, Inc. (FDMT)0.99%$874.13M-97.91%-32,380.00%30.50
Beam Therapeutics, Inc. (BEAM)0.93%$2.10B-41.48%52.63%3.08
Evotec SE (EVO)0.90%$1.27B5.80%8.64%2.22
BioNTech SE (BNTX)0.90%$27.49B-24.09%53.54%2.84
Arvinas, Inc. (ARVN)0.84%$1.71B40.37%97.78%7.31
Verve Therapeutics, Inc. (VERV)0.82%$466.28M219.73%75.09%-4.48
Editas Medicine, Inc. (EDIT)0.81%$320.01M-82.23%-176.80%2.15
Relay Therapeutics, Inc. (RLAY)0.72%$1.23B-100.00%N/A6.49
Adaptive Biotechnologies Corp. (ADPT)0.72%$679.85M-11.72%48.83%2.77
Caribou Biosciences, Inc. (CRBU)0.69%$187.95M-7.75%75.29%-2.60
Lyell Immunopharma, Inc. (LYEL)0.69%$345.60M-51.85%-37,600.00%-1,121.68
Vir Biotechnology, Inc. (VIR)0.66%$1.07B-19.02%-40.23%2.05
Century Therapeutics, Inc. (IPSC)0.65%$139.78M678.79%-349.03%33.94
Seer, Inc. (California) (SEER)0.64%$101.57M-23.35%7.45%-10.21
Moderna, Inc. (MRNA)0.60%$26.85B-29.94%35.27%7.61
AbCellera Biologics, Inc. (ABCL)0.48%$810.33M-27.18%-419.42%7.49
Prime Medicine, Inc. (PRME)0.33%$477.72MN/AN/A831.38
SAGE Therapeutics, Inc. (SAGE)0.33%$463.37M249.80%83.74%0.11
Seres Therapeutics, Inc. (MCRB)0.32%$160.00M-100.00%N/A671.28
Ginkgo Bioworks Holdings, Inc. (DNA)0.18%$319.39M-30.24%44.76%2.21
Market data by FactSet