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The Lux Bio + Tech Index



Index Performance




Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingCustom
  • # of holdings54
What's inside?


All holdings as of September 27, 2023
CSV download
BridgeBio Pharma, Inc. (BBIO)8.32%$4.319B-97.77%-17.98%723.08x
Schrödinger, Inc. (SDGR)3.61%$1.721B-8.53%39.25%17.10x
Tango Therapeutics, Inc. (TNGX)3.56%$1.126B152.95%89.67%0.64x
Recursion Pharmaceuticals, Inc. (RXRX)3.25%$1.545B43.56%0.32%22.97x
Nuvalent, Inc. (NUVL)3.23%$2.171BN/AN/AN/A
Third Harmonic Bio, Inc. (THRD)3.23%$0.252BN/AN/AN/A
10X Genomics, Inc. (TXG)2.94%$4.223B28.10%61.08%10.95x
Evotec SE (EVO)2.83%N/A1.12%27.20%4.94x
Alector, Inc. (ALEC)2.60%$0.539B-29.60%96.03%-0.85x
Ionis Pharmaceuticals, Inc. (IONS)2.57%$6.633B40.82%95.63%8.71x
Sana Biotechnology, Inc. (SANA)2.43%$0.742BN/AN/AN/A
ProKidney Corp. (DNAC)2.41%$0.266BN/AN/AN/A
Roivant Sciences Ltd. (ROIV)2.35%$9.577B400.67%56.98%90.73x
Regeneron Pharmaceuticals, Inc. (REGN)2.25%$88.852B10.53%83.91%5.97x
Verve Therapeutics, Inc. (VERV)2.25%$0.828BN/A-44.58%142.89x
Janux Therapeutics, Inc. (JANX)2.20%$0.459B-55.31%55.44%28.15x
Certara, Inc. (CERT)2.13%$2.221B9.29%47.85%8.43x
CRISPR Therapeutics AG (CRSP)2.12%$3.662B44,203.80%29.15%17.15x
ATAI Life Sciences NV (ATAI)2.10%$0.211B1.18%-13.37%222.37x
Denali Therapeutics, Inc. (DNLI)2.02%$2.939B460.45%99.54%8.81x
Nuvation Bio, Inc. (NUVB)2.01%$0.304BN/AN/AN/A
Nurix Therapeutics, Inc. (NRIX)1.98%$0.411B168.33%89.13%4.55x
Exscientia Plc (EXAI)1.92%$0.575B-57.96%-230.07%9.47x
Ginkgo Bioworks Holdings, Inc. (DNA)1.92%$2.770B-44.29%55.63%8.83x
Intellia Therapeutics, Inc. (NTLA)1.90%$2.863B-3.11%84.04%52.99x
Compass Pathways Plc (CMPS)1.83%$0.483BN/AN/AN/A
Caribou Biosciences, Inc. (CRBU)1.83%$0.433B-10.42%70.01%2.04x
Editas Medicine, Inc. (EDIT)1.77%$0.576B-54.62%46.66%9.97x
Dyne Therapeutics, Inc. (DYN)1.76%$0.550BN/AN/AN/A
SomaLogic, Inc. (SLGC)1.21%$0.440B44.71%45.40%-0.40x
Nkarta, Inc. (NKTX)1.19%$0.082BN/AN/AN/A
EQRx, Inc. (EQRX)1.11%$1.077BN/AN/AN/A
SAGE Therapeutics, Inc. (SAGE)1.11%$1.248B64.82%78.33%175.13x
Olink Holding AB (OLK)1.08%$1.806B6.93%58.74%14.97x
Beam Therapeutics, Inc. (BEAM)1.07%$1.869B20.80%63.76%19.23x
Adaptive Biotechnologies Corp. (ADPT)1.06%$0.804B12.06%51.84%4.13x
Moderna, Inc. (MRNA)1.04%$37.344B-92.71%-138.66%3.70x
Ultragenyx Pharmaceutical, Inc. (RARE)1.01%$2.674B21.23%90.85%9.05x
Alnylam Pharmaceuticals, Inc. (ALNY)0.99%$21.881B41.78%73.22%19.61x
AbCellera Biologics, Inc. (ABCL)0.98%$1.360B-78.10%27.84%7.78x
Lyell Immunopharma, Inc. (LYEL)0.97%$0.387B-99.92%-16,711.11%5.49x
Century Therapeutics, Inc. (IPSC)0.96%$0.121B-92.91%-2,333.33%15.96x
BioNTech SE (BNTX)0.96%$24.754B-94.63%2.86%1.13x
Relay Therapeutics, Inc. (RLAY)0.95%$1.016B-67.40%-1,021.01%756.31x
Seer, Inc. (California) (SEER)0.95%$0.134B10.69%23.03%-1.17x
Fate Therapeutics, Inc. (FATE)0.95%$0.199B-94.97%-378.67%1.65x
Vir Biotechnology, Inc. (VIR)0.94%$1.242BN/A-84.30%3.18x
Prime Medicine, Inc. (PRME)0.94%$0.997BN/AN/AN/A
Erasca, Inc. (ERAS)0.93%$0.320BN/AN/AN/A
4D Molecular Therapeutics, Inc. (FDMT)0.93%$0.553B47.53%-497.49%174.26x
Kymera Therapeutics, Inc. (KYMR)0.87%$0.849B43.42%94.55%20.29x
Seres Therapeutics, Inc. (MCRB)0.83%$0.299B10,300.74%97.07%4.64x
Arvinas, Inc. (ARVN)0.83%$1.116B74.12%97.06%1.84x
Stoke Therapeutics, Inc. (STOK)0.82%$0.172B-176.79%N/A27.38x
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