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LUX CAPITAL
The Lux Bio + Tech Index

LUXBT

Index Performance

-11.30%
LUXBT
-2.87%
IBB
+10.18%
SPY

Overview

Description

Developed by Lux Capital, the Lux Bio + Tech Index™ is a secular investment theme that covers companies innovating to further the molecular understanding of the "omics stack" to companies building "operating systems" for the future of drug discovery and ultimately even drug development. Over time these companies have transformed from radical, even heretical, ideas to undeniable technical, scientific, and clinical proof points. The last decade has ushered in an unparalleled understanding of the molecular basis of biology, enabled by emergent tool kits to engineer and perturb biology, ultimately increasing the velocity of discovery. Today, Moore's Law-like cost curves exist along many axes in biotech and have given rise to an era of precise, high fidelity, large scale, highly reproducible, and increasingly automated biological and chemical experimentation and discovery. The modern scientist-entrepreneur not only sits at the wetbench but also has proficiency to deconvolute high dimensional and historically unmanageable data with GPUs, the cloud, and the array of advances from machine learning and deep learning.

Full methodology
  • TickerLUXBT
  • Inception Date04/23/2021
  • WeightingEqual
  • # of holdings44
What's inside?

Holdings

All holdings as of December 10, 2024
CSV download
Recursion Pharmaceuticals, Inc. (RXRX)5.74%$2.90B147.62%37.97%23.37
Janux Therapeutics, Inc. (JANX)3.21%$3.60B-82.56%-16.17%141.56
Evotec SE (EVO)3.16%$1.65B-4.87%9.89%1.76
Verve Therapeutics, Inc. (VERV)3.12%$568.94M120.24%74.45%-2.42
Beam Therapeutics, Inc. (BEAM)2.99%$2.50B-17.01%61.63%3.59
Schrödinger, Inc. (SDGR)2.93%$1.61B-17.10%50.24%5.55
Adaptive Biotechnologies Corp. (ADPT)2.82%$990.26M22.46%58.81%4.15
AbCellera Biologics, Inc. (ABCL)2.80%$892.01M-1.39%-488.52%5.15
Erasca, Inc. (ERAS)2.70%$836.87MN/AN/AN/A
BridgeBio Pharma, Inc. (BBIO)2.67%$5.49B-33.22%32.80%28.17
Stoke Therapeutics, Inc. (STOK)2.61%$702.34M47.94%77.30%27.38
Nuvation Bio, Inc. (NUVB)2.61%$914.81MN/A-130.67%40.94
CRISPR Therapeutics AG (CRSP)2.49%$4.16BN/A-2,550.00%11.32
Roivant Sciences Ltd. (ROIV)2.46%$8.80B-87.94%94.77%28.46
Kymera Therapeutics, Inc. (KYMR)2.43%$2.92B-20.88%46.54%35.87
Certara, Inc. (CERT)2.43%$1.87B10.80%46.66%5.26
Vir Biotechnology, Inc. (VIR)2.42%$1.11B-9.81%-23.78%1.68
Ionis Pharmaceuticals, Inc. (IONS)2.34%$6.04B-7.21%95.09%6.79
Third Harmonic Bio, Inc. (THRD)2.33%$567.29MN/AN/AN/A
Revolution Medicines, Inc. (RVMD)2.32%$8.62BN/AN/A8,225.88
Nurix Therapeutics, Inc. (NRIX)2.30%$1.56B-31.84%67.06%25.04
Rapport Therapeutics, Inc. (RAPP)2.29%$749.82MN/AN/AN/A
Arvinas, Inc. (ARVN)2.28%$1.69B195.95%N/A4.07
BioNTech SE (BNTX)2.21%$28.01B40.41%85.63%3.23
Alnylam Pharmaceuticals, Inc. (ALNY)2.20%$32.75B-33.26%82.85%16.86
CG Oncology, Inc. (CGON)2.13%$2.28BN/A51.16%2,935.36
Prime Medicine, Inc. (PRME)2.13%$422.34MN/A-645.45%411.51
Ultragenyx Pharmaceutical, Inc. (RARE)2.12%$4.53B42.27%78.65%10.71
Nuvalent, Inc. (NUVL)2.05%$6.61BN/AN/AN/A
Dyne Therapeutics, Inc. (DYN)2.02%$2.88BN/AN/AN/A
Denali Therapeutics, Inc. (DNLI)1.98%$3.52B-100.00%N/AN/A
SAGE Therapeutics, Inc. (SAGE)1.95%$340.74M337.08%55.54%-1.12
Intellia Therapeutics, Inc. (NTLA)1.90%$1.50B-24.02%71.38%35.26
10X Genomics, Inc. (TXG)1.87%$1.96B-1.30%69.50%3.83
Regeneron Pharmaceuticals, Inc. (REGN)1.78%$85.55B10.65%83.53%8.31
Compass Pathways Plc (CMPS)1.70%$310.63MN/AN/AN/A
4D Molecular Therapeutics, Inc. (FDMT)1.68%$334.69M-99.99%-56,666.67%5.96
Fate Therapeutics, Inc. (FATE)1.64%$259.68M58.13%-49.87%15.93
Moderna, Inc. (MRNA)1.60%$15.97B1.69%69.60%4.17
Relay Therapeutics, Inc. (RLAY)1.57%$741.51M-100.00%N/A20.29
Sana Biotechnology, Inc. (SANA)1.36%$553.71MN/AN/AN/A
Alector, Inc. (ALEC)1.11%$216.43M68.43%85.72%0.52
Tango Therapeutics, Inc. (TNGX)1.10%$355.55M8.15%94.64%13.37
BioAge Labs, Inc. (BIOA)0.47%$152.86MN/AN/AN/A
Market data by FactSet