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Oncology Breakthrough Investment Fund

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Index Performance

-20.75%
Oncology Breakthrough Investment Fund
-4.74%
TMLARGE

Overview

Description

The pharmaceutical industry focusing on cancer treatment is propelled by developments in medical research, an aging global population, and increasing cancer incidence rates. Significant investment in R&D is leading to breakthroughs in targeted therapies and immunotherapies, which are changing the landscape of cancer care. Regulatory support and expedited approval processes for cancer drugs further enhance investment prospects. Additionally, advancements in personalized medicine and genomic technologies are driving the creation of novel, more effective treatments tailored to individual patients' genetic profiles. - [[Immunotherapy]]: Advanced cancer treatments that use the body's immune system to fight cancer cells. - [[Targeted therapy]]: Drugs designed to target specific genes or proteins that contribute to cancer growth and survival. - [[Gene editing technologies]]: Innovative approaches like CRISPR-Cas9 that aim to correct genetic mutations responsible for cancer. - [[Biopharmaceuticals]]: Use of biological sources, such as proteins and monoclonal antibodies, to develop cancer treatments. - [[Radiopharmaceuticals]]: Drugs that contain radioactive substances and are used in the diagnosis and treatment of various cancers. This index was generated with help from Thematic Analyst.

  • Inception Date07/23/2024
  • WeightingEqual
  • # of holdings21
What's inside?

Holdings

All holdings as of March 25, 2025
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IGM Biosciences, Inc. (IGMS)5.04%$75.32M25.77%-240.13%86.22
Meta Platforms, Inc. (META)5.00%$1.59T21.94%81.68%9.13
Amazon.com, Inc. (AMZN)4.99%$2.18T10.99%48.85%3.75
Alphabet, Inc. (GOOGL)4.95%$2.09T13.89%58.18%6.54
C4 Therapeutics, Inc. (CCCC)4.90%$154.76M71.44%77.82%1.98
NVIDIA Corp. (NVDA)4.88%$2.94T114.20%74.99%24.27
Apple, Inc. (AAPL)4.88%$3.36T3.95%46.88%9.89
Taiwan Semiconductor Manufacturing Co., Ltd. (TSM)4.88%$777.04B29.94%54.74%10.91
ALX Oncology Holdings, Inc. (ALXO)4.83%$38.29MN/AN/AN/A
Revolution Medicines, Inc. (RVMD)4.81%$7.15B-100.00%N/AN/A
Centessa Pharmaceuticals Plc (CNTA)4.78%$2.10B-100.00%N/AN/A
Neoleukin Therapeutics, Inc. (NLTX)4.76%$210.94MN/A-251.03%109.84
Schrödinger, Inc. (SDGR)4.69%$1.57B-4.21%63.64%5.55
Insmed, Inc. (INSM)4.68%$14.22B19.17%75.04%30.81
PharmaEngine, Inc. (4162)4.67%$451.26M228.70%98.11%3.62
Bicycle Therapeutics Plc (BCYC)4.64%$611.19M30.31%79.66%-1.56
Erasca, Inc. (ERAS)4.61%$419.23MN/AN/AN/A
Oric Pharmaceuticals, Inc. (ORIC)4.57%$479.43MN/AN/AN/A
Springworks Therapeutics, Inc. (SWTX)4.51%$3.54B3,417.33%91.95%12.41
Arcus Biosciences, Inc. (RCUS)4.48%$889.07M120.51%96.12%2.03
Geron Corp. (GERN)4.45%$1.08B32,386.92%98.37%27.60
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