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BIOTECH MDB INDEX

BMDB

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Index Performance

+32.85%
BMDB
+5.50%
TMLARGE

Overview

Description

Follow Biotechnology and pharma companies with a market cap between $30 million and $400 million.

  • TickerBMDB
  • Inception Date12/07/2023
  • WeightingEqual
  • # of holdings91
What's inside?

Holdings

All holdings as of December 12, 2025
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Galecto, Inc. (GLTO)8.84%$42.47MN/AN/AN/A
Cypherpunk Technologies, Inc. (LPTX)3.95%$81.58MN/AN/AN/A
Mersana Therapeutics, Inc. (MRSN)3.12%$141.71M-12.61%99.25%-0.48
Cidara Therapeutics, Inc. (CDTX)2.56%$6.94BN/AN/AN/A
Relmada Therapeutics, Inc. (RLMD)2.12%$297.73MN/AN/AN/A
Kodiak Sciences, Inc. (KOD)2.00%$1.26BN/AN/AN/A
CytomX Therapeutics, Inc. (CTMX)1.69%$709.93M-82.16%97.75%3.42
AlloVir, Inc. (ALVR)1.57%$165.89MN/AN/AN/A
Minerva Neurosciences, Inc. (NERV)1.53%$27.13MN/AN/AN/A
Astria Therapeutics, Inc. (ATXS)1.47%$738.11MN/AN/A416.92
Verrica Pharmaceuticals, Inc. (VRCA)1.45%$75.16MN/A92.27%1.80
Annovis Bio, Inc. (ANVS)1.44%$109.46MN/AN/AN/A
Axogen, Inc. (AXGN)1.42%$1.40B23.51%76.55%4.21
Annexon, Inc. (ANNX)1.40%$719.30MN/AN/AN/A
Acumen Pharmaceuticals, Inc. (ABOS)1.36%$129.63MN/AN/AN/A
Achieve Life Sciences, Inc. (ACHV)1.32%$247.01MN/AN/AN/A
NeuroPace, Inc. (NPCE)1.31%$539.25M29.89%77.39%3.72
Trevi Therapeutics, Inc. (TRVI)1.26%$1.64BN/AN/AN/A
Opus Genetics, Inc. (OCUP)1.25%$162.76M-20.38%99.58%5.93
Atara Biotherapeutics, Inc. (ATRA)1.20%$129.75M-91.41%96.67%1.57
Assembly Biosciences, Inc. (ASMB)1.19%$571.00M57.62%99.70%2.55
Esperion Therapeutics, Inc. (ESPR)1.17%$920.39M69.10%52.71%3.41
SOPHiA GENETICS SA (SOPH)1.15%$322.27M22.77%66.32%4.15
Vistagen Therapeutics, Inc. (VTGN)1.14%$167.86M40.98%28.29%106.17
Mind Medicine (MindMed), Inc. (MNMD)1.12%$1.24BN/AN/AN/A
Vanda Pharmaceuticals, Inc. (VNDA)1.12%$368.17M18.06%91.63%0.06
DiaMedica Therapeutics, Inc. (DMAC)1.11%$489.01MN/AN/AN/A
Oramed Pharmaceuticals, Inc. (ORMP)1.06%$122.19MN/AN/A-10.93
Galectin Therapeutics, Inc. (GALT)1.05%$403.00MN/AN/AN/A
KalVista Pharmaceuticals, Inc. (KALV)1.04%$854.74MN/A91.00%41.65
Karyopharm Therapeutics, Inc. (KPTI)1.04%$118.50M13.57%94.93%1.45
AC Immune SA (ACIU)1.03%$311.67M-96.01%N/A31.27
Sol-Gel Technologies Ltd. (SLGL)1.03%$108.67M-92.54%N/A3.24
SELLAS Life Sciences Group, Inc. (SLS)1.00%$289.16MN/AN/AN/A
ADC Therapeutics SA (ADCT)1.00%$524.00M-11.03%91.95%10.22
VYNE Therapeutics, Inc. (VYNE)0.99%$12.50M39.67%96.45%-35.04
MediciNova, Inc. (MNOV)0.98%$75.69MN/A-31.59%116.24
Neoleukin Therapeutics, Inc. (NLTX)0.98%$309.10MN/AN/AN/A
Whitehawk Therapeutics, Inc. (AADI)0.97%$109.34M-100.00%N/A-2.16
Cognition Therapeutics, Inc. (CGTX)0.97%$149.18MN/AN/AN/A
Ocular Therapeutix, Inc. (OCUL)0.97%$3.10B-5.71%87.80%33.74
Lifeward Ltd. (RWLK)0.97%$12.38M1.09%43.70%0.39
Rigel Pharmaceuticals, Inc. (RIGL)0.95%$740.21M25.59%93.16%1.65
Daré Bioscience, Inc. (DARE)0.94%$35.29M-94.57%-26,993.90%1,213.62
Cardiff Oncology, Inc. (CRDF)0.94%$160.99M-27.27%-86.67%156.07
Spero Therapeutics, Inc. (SPRO)0.93%$130.71M-61.02%N/A2.07
Solid Biosciences, Inc. (SLDB)0.92%$457.33MN/AN/AN/A
Sutro Biopharma, Inc. (STRO)0.90%$83.75M13.77%80.40%1.27
ProQR Therapeutics NV (PRQR)0.90%$245.15M-20.23%76.72%6.80
Atea Pharmaceuticals, Inc. (AVIR)0.88%$246.10MN/AN/AN/A
GlycoMimetics, Inc. (GLYC)0.88%$195.75MN/AN/AN/A
Lexicon Pharmaceuticals, Inc. (LXRX)0.88%$472.42M710.40%98.86%6.20
Anixa Biosciences, Inc. (ANIX)0.87%$117.84MN/AN/AN/A
Verastem, Inc. (VSTM)0.86%$723.82MN/A82.57%44.68
Precision BioSciences, Inc. (DTIL)0.84%$120.12M-97.74%-5,084.62%70.91
Voyager Therapeutics, Inc. (VYGR)0.83%$244.08M-45.73%93.03%3.32
CorMedix, Inc. (CRMD)0.83%$905.29M810.22%89.26%4.44
Ocugen, Inc. (OCGN)0.82%$424.76M54.23%45.78%92.35
Abeona Therapeutics, Inc. (ABEO)0.81%$290.47MN/AN/A257.63
Nektar Therapeutics (NKTR)0.80%$1.11B-51.13%98.34%15.57
Precigen, Inc. (PGEN)0.80%$1.31B206.61%53.70%156.55
Larimar Therapeutics, Inc. (LRMR)0.78%$346.64MN/AN/AN/A
Vivani Medical, Inc. (EYES)0.77%$98.49MN/AN/AN/A
electroCore, Inc. (ECOR)0.77%$37.98M32.58%85.97%1.32
Actinium Pharmaceuticals, Inc. (ATNM)0.77%$47.11MN/A-128.89%-25.94
PMV Pharmaceuticals, Inc. (PMVP)0.76%$65.45MN/AN/AN/A
PDS Biotechnology Corp. (PDSB)0.75%$53.30MN/AN/AN/A
Aldeyra Therapeutics, Inc. (ALDX)0.74%$273.14MN/AN/AN/A
Delcath Systems, Inc. (DCTH)0.73%$366.20M83.60%87.24%4.30
Inovio Pharmaceuticals, Inc. (INO)0.72%$141.53MN/AN/A445.83
Enlivex Therapeutics Ltd. (ENLV)0.72%$22.57MN/AN/AN/A
XBiotech, Inc. (XBIT)0.71%$73.17MN/AN/AN/A
Syros Pharmaceuticals, Inc. (SYRS)0.67%$0.01M-33.23%N/A14.41
InspireMD, Inc. (NSPR)0.65%$82.62M39.39%34.24%15.04
InflaRx NV (IFRX)0.64%$70.49M-79.53%-320.17%220.06
aTyr Pharma, Inc. (LIFE)0.63%$75.99MN/A-104.74%-41.83
BioVie, Inc. (BIVI)0.63%$10.93MN/AN/AN/A
IRIDEX Corp. (IRIX)0.63%$15.83M7.80%32.15%0.49
Exagen, Inc. (XGN)0.60%$161.13M37.87%58.43%3.85
SIGA Technologies, Inc. (SIGA)0.60%$462.61M-73.83%61.75%2.81
Immunic, Inc. (IMUX)0.60%$74.76MN/AN/AN/A
CollPlant Biotechnologies Ltd. (CLGN)0.59%$23.02M1,825.00%-538.96%11.45
Cellectar Biosciences, Inc. (CLRB)0.57%$15.35MN/AN/AN/A
Curis, Inc. (CRIS)0.55%$15.00M8.36%98.52%4.08
Immuneering Corp. (IMRX)0.54%$392.59MN/AN/AN/A
Akebia Therapeutics, Inc. (AKBA)0.48%$440.51M57.01%83.49%3.53
SCYNEXIS, Inc. (SCYX)0.47%$27.11M-49.39%N/A0.92
Lyra Therapeutics, Inc. (LYRA)0.47%$6.45M-87.18%-300.00%34.77
Tempest Therapeutics, Inc. (TPST)0.26%$15.32MN/AN/AN/A
Carisma Therapeutics, Inc. (SESN)0.19%$2.33M1,236.78%N/A0.18
CARA Therapeutics, Inc. (CARA)0.10%$41.36M-100.00%N/A81.81
Market data by FactSet

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