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BIOTECH MDB INDEX

BMDB

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Index Performance

+36.04%
BMDB
+4.49%
TMLARGE

Overview

Description

Follow Biotechnology and pharma companies with a market cap between $30 million and $400 million.

  • TickerBMDB
  • Inception Date12/07/2023
  • WeightingEqual
  • # of holdings91
What's inside?

Holdings

All holdings as of December 15, 2025
CSV download
Galecto, Inc. (GLTO)8.90%$41.94MN/AN/AN/A
Cypherpunk Technologies, Inc. (LPTX)3.36%$67.98MN/AN/AN/A
Mersana Therapeutics, Inc. (MRSN)3.21%$142.91M-12.61%99.25%-0.48
Cidara Therapeutics, Inc. (CDTX)2.61%$6.92BN/AN/AN/A
Relmada Therapeutics, Inc. (RLMD)2.32%$319.73MN/AN/AN/A
Kodiak Sciences, Inc. (KOD)1.97%$1.22BN/AN/AN/A
CytomX Therapeutics, Inc. (CTMX)1.70%$699.77M-82.16%97.75%3.42
Minerva Neurosciences, Inc. (NERV)1.63%$28.25MN/AN/AN/A
AlloVir, Inc. (ALVR)1.54%$158.97MN/AN/AN/A
Astria Therapeutics, Inc. (ATXS)1.50%$737.54MN/AN/A416.92
Axogen, Inc. (AXGN)1.42%$1.37B23.51%76.55%4.21
Verrica Pharmaceuticals, Inc. (VRCA)1.41%$71.74MN/A92.27%1.80
Annexon, Inc. (ANNX)1.41%$710.62MN/AN/AN/A
Annovis Bio, Inc. (ANVS)1.34%$100.18MN/AN/AN/A
Acumen Pharmaceuticals, Inc. (ABOS)1.34%$124.78MN/AN/AN/A
NeuroPace, Inc. (NPCE)1.31%$530.26M29.89%77.39%3.72
Achieve Life Sciences, Inc. (ACHV)1.31%$239.02MN/AN/AN/A
Trevi Therapeutics, Inc. (TRVI)1.27%$1.62BN/AN/AN/A
Atara Biotherapeutics, Inc. (ATRA)1.22%$129.42M-91.41%96.67%1.57
Vanda Pharmaceuticals, Inc. (VNDA)1.21%$391.81M18.06%91.63%0.06
Vistagen Therapeutics, Inc. (VTGN)1.21%$173.39M40.98%28.29%106.17
Esperion Therapeutics, Inc. (ESPR)1.17%$903.66M69.10%52.71%3.41
SOPHiA GENETICS SA (SOPH)1.17%$320.24M22.77%66.32%4.15
Assembly Biosciences, Inc. (ASMB)1.16%$547.27M57.62%99.70%2.55
Sol-Gel Technologies Ltd. (SLGL)1.15%$119.15M-92.54%N/A3.24
Opus Genetics, Inc. (OCUP)1.15%$146.89M-20.38%99.58%5.93
Galectin Therapeutics, Inc. (GALT)1.12%$419.76MN/AN/AN/A
Mind Medicine (MindMed), Inc. (MNMD)1.10%$1.19BN/AN/AN/A
AC Immune SA (ACIU)1.09%$320.58M-96.01%N/A31.27
Oramed Pharmaceuticals, Inc. (ORMP)1.08%$122.59MN/AN/A-10.93
KalVista Pharmaceuticals, Inc. (KALV)1.06%$854.23MN/A91.00%41.65
DiaMedica Therapeutics, Inc. (DMAC)1.04%$451.51MN/AN/AN/A
SELLAS Life Sciences Group, Inc. (SLS)1.03%$290.58MN/AN/AN/A
Karyopharm Therapeutics, Inc. (KPTI)1.02%$114.41M13.57%94.93%1.45
ADC Therapeutics SA (ADCT)1.01%$521.52M-11.03%91.95%10.22
Whitehawk Therapeutics, Inc. (AADI)1.01%$111.22M-100.00%N/A-2.16
Rigel Pharmaceuticals, Inc. (RIGL)1.01%$771.07M25.59%93.16%1.65
MediciNova, Inc. (MNOV)0.98%$74.70MN/A-31.59%116.24
VYNE Therapeutics, Inc. (VYNE)0.97%$11.98M39.67%96.45%-35.04
Cardiff Oncology, Inc. (CRDF)0.97%$162.34M-27.27%-86.67%156.07
Neoleukin Therapeutics, Inc. (NLTX)0.96%$299.35MN/AN/AN/A
Ocular Therapeutix, Inc. (OCUL)0.96%$3.02B-5.71%87.80%33.74
ProQR Therapeutics NV (PRQR)0.96%$257.77M-20.23%76.72%6.80
Spero Therapeutics, Inc. (SPRO)0.94%$129.02M-61.02%N/A2.07
Cognition Therapeutics, Inc. (CGTX)0.94%$141.24MN/AN/AN/A
Sutro Biopharma, Inc. (STRO)0.92%$84.60M13.77%80.40%1.27
Solid Biosciences, Inc. (SLDB)0.92%$444.87MN/AN/AN/A
Lifeward Ltd. (RWLK)0.91%$11.37M1.09%43.70%0.39
Atea Pharmaceuticals, Inc. (AVIR)0.90%$246.10MN/AN/AN/A
Daré Bioscience, Inc. (DARE)0.89%$32.58M-94.57%-26,993.90%1,213.62
Lexicon Pharmaceuticals, Inc. (LXRX)0.85%$446.98M710.40%98.86%6.20
Ocugen, Inc. (OCGN)0.85%$431.00M54.23%45.78%92.35
Verastem, Inc. (VSTM)0.84%$698.21MN/A82.57%44.68
GlycoMimetics, Inc. (GLYC)0.84%$183.52MN/AN/AN/A
Voyager Therapeutics, Inc. (VYGR)0.84%$242.42M-45.73%93.03%3.32
Precigen, Inc. (PGEN)0.84%$1.35B206.61%53.70%156.55
CorMedix, Inc. (CRMD)0.83%$892.68M810.22%89.26%4.44
Actinium Pharmaceuticals, Inc. (ATNM)0.83%$49.60MN/A-128.89%-25.94
Precision BioSciences, Inc. (DTIL)0.83%$115.54M-97.74%-5,084.62%70.91
Inovio Pharmaceuticals, Inc. (INO)0.81%$155.27MN/AN/A445.83
Anixa Biosciences, Inc. (ANIX)0.81%$107.31MN/AN/AN/A
Nektar Therapeutics (NKTR)0.80%$1.08B-51.13%98.34%15.57
electroCore, Inc. (ECOR)0.79%$38.14M32.58%85.97%1.32
Vivani Medical, Inc. (EYES)0.79%$98.49MN/AN/AN/A
Abeona Therapeutics, Inc. (ABEO)0.78%$275.29MN/AN/A257.63
Larimar Therapeutics, Inc. (LRMR)0.77%$335.51MN/AN/AN/A
XBiotech, Inc. (XBIT)0.77%$77.13MN/AN/AN/A
PMV Pharmaceuticals, Inc. (PMVP)0.76%$63.85MN/AN/AN/A
Delcath Systems, Inc. (DCTH)0.72%$355.96M83.60%87.24%4.30
PDS Biotechnology Corp. (PDSB)0.72%$50.27MN/AN/AN/A
IRIDEX Corp. (IRIX)0.69%$16.96M7.80%32.15%0.49
Syros Pharmaceuticals, Inc. (SYRS)0.68%$0.01M-33.23%N/A14.41
Enlivex Therapeutics Ltd. (ENLV)0.68%$20.92MN/AN/AN/A
Aldeyra Therapeutics, Inc. (ALDX)0.67%$240.05MN/AN/AN/A
InspireMD, Inc. (NSPR)0.67%$83.47M39.39%34.24%15.04
BioVie, Inc. (BIVI)0.64%$10.78MN/AN/AN/A
InflaRx NV (IFRX)0.62%$67.13M-79.53%-320.17%220.06
aTyr Pharma, Inc. (LIFE)0.61%$71.86MN/A-104.74%-41.83
Exagen, Inc. (XGN)0.61%$159.32M37.87%58.43%3.85
Immunic, Inc. (IMUX)0.60%$73.82MN/AN/AN/A
SIGA Technologies, Inc. (SIGA)0.60%$452.58M-73.83%61.75%2.81
Curis, Inc. (CRIS)0.58%$15.39M8.36%98.52%4.08
CollPlant Biotechnologies Ltd. (CLGN)0.55%$21.24M1,825.00%-538.96%11.45
Immuneering Corp. (IMRX)0.52%$373.21MN/AN/AN/A
Lyra Therapeutics, Inc. (LYRA)0.51%$6.98M-87.18%-300.00%34.77
Cellectar Biosciences, Inc. (CLRB)0.51%$13.57MN/AN/AN/A
SCYNEXIS, Inc. (SCYX)0.48%$26.76M-49.39%N/A0.92
Akebia Therapeutics, Inc. (AKBA)0.48%$427.24M57.01%83.49%3.53
Tempest Therapeutics, Inc. (TPST)0.25%$14.49MN/AN/AN/A
Carisma Therapeutics, Inc. (SESN)0.16%$1.99M1,236.78%N/A0.18
CARA Therapeutics, Inc. (CARA)0.10%$39.58M-100.00%N/A81.81
Market data by FactSet

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